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Here's an interesting link from Stanford University about the
1918-1919 Spanish Flu.

http://virus.stanford.edu/uda

Years ago, I had an older neighbor, who as a boy worked as a pharmacy
delivery boy during the 1918 flu epidemic. He said he would ride
through the neighborhoods here in Sacramento, and literally toss
medications up onto the porches from the curb. Much like a paper boy
does today. The reason - there were "Quarantine" signs on the doors
and houses.

I don't know how many souls were lost in Sacramento, but do know that
a visit to our local cemetaries has an abundance of tomb stones with
1918 listed as dates of death.

I understand that NYC lost 1/3 of it's population!